Hyperlipidemia and mixed dyslipidemia as adjunctive therapy to diet to reduce elevated Total-C, LDL-C,
ApoB, nonHDL-C, and triglycerides and to increase HDL-C in adult patients with primary hyperlipidemia or mixed dyslipidemia. Lipid altering agents should be used in addition to a diet restricted in saturated fat and cholesterol when response to diet and nonpharmacological interventions alone has been inadequate.
Pediatric patients 10 to 17 years of age with heterozygous familal hypercholesterolemia (HeFH) as adjunct to diet to reduce Total-C, LDL-C and ApoB levels in adolescent boys and girls, who are at least one year postmenarche, 10-17 years of age with heterozygous familial hypercholesterolemia if after an adequate trial of diet therapy the following findings are present: LDL-C greater than 190 mg/dL or greater than 160 mg/dL and there is a positive family his tory of premature cardiovascular disease (CVD) or two or more other CVD risk factors.