Treatment of hypertension in adults and children 1 to < 17 years of age. It may be used alone or in
combination with other antihypertensive agents.
Treatment of heart failure (NYHA class II-IV) in adults with left ventricular systolic dysfunction
(< 40%) to reduce cardiovascular death and to reduce heart failurehospitalizations. Has an added effect on these outcomes when used with an ACE inhibitor.